Table 4 Proportion of events, Mantel-Haenszel hazard ratios, 10-year overall survival rates, confidence intervals and p values stratified by the score based on the three comorbidity classifications with complementary information content ASA class, Charlson score and body mass index in the whole sample and subdivided into age groups

0

12/137

1

91.5%

84.7-95.4%

1

47/450

1.44

0.81-2.56

0.2133

90.5%

86.7-93.3%

2

23/253

1.30

0.65-2.57

0.4582

90.9%

85.4-94.4%

3

22/125

2.70

1.35-5.39

0.0049

80.3%

69.6-87.6%

4

11/61

2.68

1.07-6.70

0.0346

82.5%

69.8-90.2%

5

6/26

7.11

1.73-29.24

0.0066

74.2%

47.2-88.8%

Age 65+ years (n = 1079)

Points

Events

Hazard ratio

95% CI

p*

10-year survival

95% CI

0

3/53

1

98.1%

87.4-99.7%

1

56/469

2.24

1.08-4.64

0.0300

88.0%

83.6-91.2%

2

46/259

2.60

1.32-5.13

0.0058

80.5%

73.5-85.8%

3

30/157

3.14

1.48-6.69

0.0030

78.2%

69.0-84.9%

4

29/106

4.07

1.98-8.37

0.0001

67.0%

54.7-76.6%

5

16/35

21.12

7.45-59.90

<0.0001

48.9%

26.2-68.3%

All patients (n = 2131)

Points

Events

Hazard ratio

95% CI

p*

10-year survival

95% CI

0

15/190

1

93.4%

88.3-96.3%

1

103/919

1.73

1.11-2.69

0.0149

89.3%

86.5-91.5%

2

69/512

2.00

1.26-3.18

0.0032

85.7%

81.4-89.0%

3

52/282

2.89

1.77-4.71

<0.0001

78.9%

72.2-84.2%

4

40/167

3.88

2.25-6.70

<0.0001

73.0%

64.2-80.0%

5

22/61

21.30

8.95-50.72

<0.0001

60.3%

43.2-73.7%