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Table 1 Patient characteristics and clinicopathological variables, and their prognostic value for the three endpoints in 535 prostate cancer patients (univariate analyses; log rank test)

From: Disease-specific outcomes of Radical Prostatectomies in Northern Norway; a case for the impact of perineural infiltration and postoperative PSA-doubling time

Characteristic Patients Patients BF CF PCD
(n) (%) (170 events) (36 events) (15 events)
   5-year EFS (%) p 10-year EFS (%) p 10-year EFS (%) p
Age     0.55   0.085   0.600
  ≤ 65 years 357 67 76   92   97  
  > 65 years 178 33 70   88   96  
pT-stage     <0.001   <0.001   0.027
  pT2 374 70 83   96   98  
  pT3a 114 21 60   86   98  
  pT3b 47 9 43   73   89  
pN-stage     <0.001   <0.001   <0.001
  NX 264 49 79   95   98  
  N0 268 50 71   89   97  
  N1 3 1 0   33   67  
Preop PSA     <0.001   0.085   0.061
  PSA < 10 308 57 80   93   99  
  PSA > 10 221 42 67   88   95  
  Missing 6 1 -   -   -  
Gleason     <0.001   <0.001   0.001
  3 + 3 183 34 83   98   99  
  3 + 4 220 41 76   93   98  
  4 + 3 80 15 69   84   95  
  4 + 4 19 4 63   76   94  
  ≥9 33 6 34   67   87  
Tumor size     <0.001   0.019   0.098
  0-20 mm 250 47 82   94   99  
  >20 mm 285 53 67   88   96  
PNI     <0.001   <0.001   0.002
  No 401 75 79   95   98  
  Yes 134 25 60   81   93  
PSM     0.041   0.038   0.697
  No 249 47 81   94   97  
  Yes 286 53 69   89   97  
Non-apical PSM     <0.001   <0.001   0.029
  No 381 71 81   95   98  
  Yes 154 29 57   81   94  
Apical PSM     0.04   0.484   0.31
  No 325 61 73   90   96  
  Yes 210 39 77   92   98  
LVI     <0.001   <0.001   0.009
  No 492 92 77   93   98  
  Yes 43 8 46   71   88  
Surgical proc     0.23   0.41   0.581
  Retropubic 435 81 76   90   97  
  Perineal 100 19 67   95   98  
  1. Abbreviations: BF biochemical failure, CF Clinical failure, EFS event free survival in months, LVI lymphovascular infiltration, PCD prostate cancer death, NR not reached, P P value for log rank statistic for difference in event free survival, PC Prostate cancer, PNI Perineural infiltration, Post op RT postoperative radiotherapy, Preop preoperative, PSA Prostate specific antigen, PSM Positive surgical margin, Surgical proc surgical procedure. Significant p-values in bold (threshold p ≤ 0.05).