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Figure 3 | BMC Urology

Figure 3

From: Panobinostat synergizes with bortezomib to induce endoplasmic reticulum stress and ubiquitinated protein accumulation in renal cancer cells

Figure 3

The combination of panobinostat and bortezomib induced apoptosis in renal cancer cells. Cells were treated for 48 hours with 50 nM panobinostat with or without 10 nM bortezomib. The combination increased the annexin-V-FITC fluorescence intensity (A) and increased the number of the cells in the sub-G1 fraction (B). Relative annexin-V-FITC fluorescence intensity (control = 1) is shown in the insets. White, control; red, treated. The percentage of cells in the sub-G1 fraction is shown in the graph. Representative results are shown.

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BMC Urology

ISSN: 1471-2490

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