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Table 1 Differences in potential predictive parameters according to the appearance of BCR

From: The use of early postoperative prostate-specific antigen to stratify risk in patients with positive surgical margins after radical prostatectomy

Parameters

BCR

BCR-free

p value

n

55

61

 

Pre-operative PSA (ng/ml, range)

9.20 (2.85-38.20)

7.60 (3.08-59.7)

0.172

Pathologic Gleason sum ≥ 7

27 (49.1%)

32 (52.5%)

0.717

Pathologic extraprostatic extension

25 (45.5%)

26 (42.6%)

0.393

Seminal vesicle invasion

8 (14.5%)

3 (5%)

0.077

PSA – day 14 (ng/ml, range)

0.298 (0.071-1.940)

0.238 (0.045-3.020)

0.264

PSA – day 30 (ng/ml, range)

0.085 (0.008-0.747)

0.022 (0.003-0.692)

<0.0001

PSA – day 60 (ng/ml, range)

0.041 (0.003-0.882)

0.010 (0.003-0.618)

<0.0001

PSA – day 90 (ng/ml, range)

0.042 (0.003-1.010)

0.008 (0.003-0.853)

<0.0001

PSA – day 180 (ng/ml, range)

0.013 (0.015-1.167)

0.011 (0.003-0.931)

<0.0001

PSA nadir (ng/ml, range)

0.022 (0.003-0.137)

0.007 (0.003-0.039)

<0.0001

Time to PSA nadir (months, range)

2 (0.5-3)

2 (1–12)

0.005

  1. BCR, biochemical recurrence; PSA, prostate specific antigen;
  2. Data presented as n (%) or median (range).