Table 2 Primary and secondary endpoints

Primary endpoint

• Changes in the IPSS 12 weeks after intervention

Secondary endpoints (see Figure 1 for time points)

• Changes in free uroflowmetry and post-void residual

• Changes in bladder diary

• Changes in urodynamic investigation

• Changes in IPSS, CPSI and IIEF

• Changes of haemoglobin and serum PSA

• Duration of post procedure catheterisation and hospitalisation

• Procedure time and radiation parameters

• Changes of prostate volume, measure of devascularized/resected tissue using MRI

• Comparison of prostate size, measured preoperatively by TRUS and MRI at baseline