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Table 1 Highly expressed Casodex responsive genes in the LNCaP model. Data show fold-increase in gene expression over reference samples. Each datum point represents mean ± SE from 3 independent experiments.

From: Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression model

  

LNCaP-R

LNCaP-UR

GenBank #

Name

Control ± SE

Treated ± SE

Control ± SE

Treated ± SE

AA663884

synaptosomal-associated protein

15.18 ± 3.35

20.67 ± 9.33

20.92 ± 1.07

11.68 ± 0.61

AA700604

sorbitol dehydrogenase

13.73 ± 3.23

19.60 ± 6.50

21.08 ± 1.58

11.08 ± 1.39

T73556

fatty-acid-Coenzyme A ligase

5.11 ± .34

2.45 ± 0.74

3.94 ± 0.46

1.07 ± 0.25

AA028987

EST

5.38 ± 6.95

8.43 ± 5.68

6.22 ± 2.05

11.00 ± 3.74

R98851

membrane metallo-endopeptidase

10.28 ± 5.90

55.90 ± 30.2

79.29 ± 16.62

153.50 ± 56.07

N68465

UDP-N-acteylglucosamine pyrophosphorylase

4.37 ± 3.73

3.99 ± 1.44

12.47 ± 2.03

9.03 ± 2.41

H84113

retinal outer segment membrane 1

8.03 ± 2.06

14.73 ± 4.93

9.79 ± 1.39

7.09 ± 0.65

AA041499

cell division cycle 4-like

11.66 ± 7.07

10.67 ± 1.84

3.47 ± 0.44

3.64 ± 1.14

AA456695

H2B histone family, member Q

4.67 ± 3.02

4.23 ± 1.14

2.56 ± 0.27

4.67 ± 1.13

R82299

S-adenosylmethionine decarboxylase 1

8.35 ± 2.23

14.84 ± 4.06

11.11 ± 2.19

6.98 ± 0.51

AA063521

BCL2/adenovirus E1B 19 kD

3.59 ± 3.34

13.14 ± 3.94

6.76 ± 1.79

12.46 ± 2.32

AA419164

retinoic acid receptor, beta

9.90 ± 3.40

11.14 ± 2.23

7.44 ± 0.98

5.01 ± 0.46

AA459039

serine protease inhibitor, Kunitz type,

2.89 ± 2.90

10.44 ± 1.46

6.28 ± 0.99

9.94 ± 1.44

AA489752

cyclin G2

2.86 ± 2.67

10.97 ± 1.10

6.92 ± 1.62

15.14 ± 4.80

AA412053

CD9 antigen (p24)

4.80 ± 1.05

8.78 ± 2.72

5.44 ± 0.96

6.12 ± 0.84