Table 1 Histopathological Findings
Gluteraldehyde cross-linked bovine collagen (Injection material) | Group IIA 3 months later (10 rats) | Group IIB 6 months later (10 rats) | Group IIC 12 months later (10 rats) | Total (30 rats) |
|---|---|---|---|---|
Fibroblasts invasion | 10 (100%) | 8 (80%) | 10 (100%) | 28 (93.3%) |
Collagen formation | 8 (80%) | 6 (60%) | 8 (80%) | 22 (73.3%) |
Capillary growth | 6 (60%) | 6 (60%) | 2 (20%) | 14 (46.6%) |
Inflammatory reaction | 0 (0%) | 6 (60%) | 0 (0%) | 6 (20%) |
Foreign body type giant cells | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Granuloma formation | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Calcification | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Migration to brain | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |