Skip to main content

Table 1 Characteristics of patients with HIV-associated bladder cancer.

From: HIV-associated bladder cancer: a case series evaluating difficulties in diagnosis and management

Case Age
(years)
Gender CD4 count (cells/mm3) HIV load (copies/mL) HAART Clinical Presentation Pathology TNM (stage)
at diagnosis
Therapy Outcome
Al Soub2
1992
49 Male 270 NR AZT only* Frequency, Dysuria,
LAP
TCC
LG
T1N0M0
(stage I)
Radiation
TURBT
Alive 1 year later
Clemente Ramos et al3
1998
33 Male 106 NR AZT only Frequency, Dysuria, Hematuria
Weight loss
TCC
HG
NR Surgery
Systemic chemotherapy
Died 5 months after diagnosis
Wolf4
2001
37 Female 318 NR No Hematuria,
LAP
TCC
HG
T1N0M0
(stage I)
TURBT
Radiation
Alive
Santos et al5 2002 51 Male 228 NR NR NR SCC NR NR Alive 4 months later
Manfredi et al6
2000
58 Male 572 1,600 Yes Hematuria TCC
LG
TaN0M0
(stage 0a)
TURBT Relapsed with local disease, Alive
Manfredi et al6
2002
57 Male 447 665,000 Yes Hematuria TCC
HG
T1N0M0
(stage I)
TURBT
Local chemotherapy
Cystectomy
Relapsed with local disease, Alive 8 months later
Case 1 61 Male 228 <50 Yes Hematuria TCC
HG
Papillary
T1N0M0
(stage I)
TURBT
Local chemotherapy
Palliative surgery and radiation
Relapsed with metastatic disease, Died 7 months later
Case 2 49 Male 280 <50 Yes Frequency, Urgency,
Dysuria, Hematuria
TCC
HG
TaN0M0
(stage 0a)
TURBT
Local chemotherapy
Cystectomy
Multiple local relapses, Alive 1 year later
Case 3 63 Male 317 50,000 Yes Hematuria TCC
HG
T3N2M1
(stage IV)
TURBT
Systemic chemotherapy
Died within 6 months
Case 4 55 Male 280 <50 Yes* Hematuria TCC
HG
T1N0M0
(stage I)
TURBT
Cystectomy
Radiation
Craniotomy
Relapsed with metastatic disease, Died 3 years after diagnosis
Case 5 67 Female 445 <50 Yes Hematuria,
LAP
TCC
HG
T4N0M0
(stage IV)
Palliative radiation
Embolization of one vesical artery
NR
  1. NR = Not reported; LAP = lower abdominal pain; TCC = Transitional cell carcinoma; SCC = Squamous cell carcinoma; HG = High grade; LG = Low grade; AZT = zidovudine; * = started after bladder cancer diagnosis; HAART = highly active antiretroviral therapy; TURBT = transurethral resection of bladder tumor