Table 1 Characteristics of patients with HIV-associated bladder cancer.
From: HIV-associated bladder cancer: a case series evaluating difficulties in diagnosis and management
Case | Age (years) | Gender | CD4 count (cells/mm3) | HIV load (copies/mL) | HAART | Clinical Presentation | Pathology | TNM (stage) at diagnosis | Therapy | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
Al Soub2 1992 | 49 | Male | 270 | NR | AZT only* | Frequency, Dysuria, LAP | TCC LG | T1N0M0 (stage I) | Radiation TURBT | Alive 1 year later |
Clemente Ramos et al3 1998 | 33 | Male | 106 | NR | AZT only | Frequency, Dysuria, Hematuria Weight loss | TCC HG | NR | Surgery Systemic chemotherapy | Died 5 months after diagnosis |
Wolf4 2001 | 37 | Female | 318 | NR | No | Hematuria, LAP | TCC HG | T1N0M0 (stage I) | TURBT Radiation | Alive |
Santos et al5 2002 | 51 | Male | 228 | NR | NR | NR | SCC | NR | NR | Alive 4 months later |
Manfredi et al6 2000 | 58 | Male | 572 | 1,600 | Yes | Hematuria | TCC LG | TaN0M0 (stage 0a) | TURBT | Relapsed with local disease, Alive |
Manfredi et al6 2002 | 57 | Male | 447 | 665,000 | Yes | Hematuria | TCC HG | T1N0M0 (stage I) | TURBT Local chemotherapy Cystectomy | Relapsed with local disease, Alive 8 months later |
Case 1 | 61 | Male | 228 | <50 | Yes | Hematuria | TCC HG Papillary | T1N0M0 (stage I) | TURBT Local chemotherapy Palliative surgery and radiation | Relapsed with metastatic disease, Died 7 months later |
Case 2 | 49 | Male | 280 | <50 | Yes | Frequency, Urgency, Dysuria, Hematuria | TCC HG | TaN0M0 (stage 0a) | TURBT Local chemotherapy Cystectomy | Multiple local relapses, Alive 1 year later |
Case 3 | 63 | Male | 317 | 50,000 | Yes | Hematuria | TCC HG | T3N2M1 (stage IV) | TURBT Systemic chemotherapy | Died within 6 months |
Case 4 | 55 | Male | 280 | <50 | Yes* | Hematuria | TCC HG | T1N0M0 (stage I) | TURBT Cystectomy Radiation Craniotomy | Relapsed with metastatic disease, Died 3 years after diagnosis |
Case 5 | 67 | Female | 445 | <50 | Yes | Hematuria, LAP | TCC HG | T4N0M0 (stage IV) | Palliative radiation Embolization of one vesical artery | NR |