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Table 1 Comparison of murine neurogenic cystitis with human IC/PBS.

From: Pharmacologic attenuation of pelvic pain in a murine model of interstitial cystitis

 

IC/PBS

Murine Cystitis

References

Pelvic Specific Pain

Yes

Yes

[1, 12, 13]

Role for mast cells

Yes

Yes

[4, 5, 12, 16, 18, 19]

Role for substance P

Yes

Yes

[7], This paper

Role for histamine

Yes

Yes

[9, 12]