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Figure 7 | BMC Urology

Figure 7

From: Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms

Figure 7

High level of PKC activation increases sensitivity of BSM strips to low frequency of EFS. A, Upper panel shows the response of the control strip to increasing frequencies of EFS whereas the lower panel represents the frequency-response curve after incubation with PDBu (1 μM). B, PDBu caused a significant leftward shift (open circles) in BSM sensitivity to EFS representative of a 5-fold increase in muscle responsiveness to EFS in the presence of high PDBu concentration (N = 5,n = 6, p ≤ 0.05).

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