Centres | A (n = 48) | B (n = 91) | C (n = 37) | D (n = 78) | E (n = 112) | F (n = 33) | G (n = 75) |
---|---|---|---|---|---|---|---|
Mean age ± SD | 72.6 ± 6.1 | 66.9 ± 7.7 | 67.3 ± 5.6 | 67.8 ± 6.7 | 67.1 ± 7.8 | 66.2 ± 6.9 | 67.6 ± 9.2 |
Missing (%): | 0.0 | 2.2 | 0.0 | 5.1 | 0.0 | 6.1 | 4.1 |
Mean BMI ± SD | 28.2 ± 5.7 | 27.3 ± 3.5 | 27.6 ± 3.8 | 28.8 ± 6.4 | 28.9 ± 4.1 | 27.6 ± 4.3 | 27.2 ± 2.9 |
Missing (%): | 0.0 | 4.4 | 0.0 | 3.8 | 0.9 | 21.2 | 4.1 |
Median PSA (ng/mL) ± IQR | 10.4 ± 15.5 | 5.7 ± 3.4 | 6.7 ± 3.7 | 7.8 ± 7.7 | 8.6 ± 12.2 | 7.0 ± 3.8 | 8.7 ± 8.2 |
Missing (%): | 2.1 | 8.8 | 0.0 | 6.4 | 0.0 | 3.0 | 1.4 |
ECOG WHO (%) | |||||||
Fully active: | 72.9 | 84.6 | 91.9 | 71.8 | 69.6 | 63.6 | 75.3 |
Restricted or worse: | 25.0 | 15.4 | 8.1 | 23.1 | 30.4 | 33.3 | 17.8 |
Missing: | 2.1 | 0.0 | 0.0 | 5.1 | 0.0 | 3.0 | 6.8 |
Primary tumour clinical stage (T) (%) | |||||||
Tx: | 0.0 | 0.0 | 0.0 | 1.3 | 1.3 | 0.0 | 0.0 |
T1a-c | 45.8 | 45.1 | 16.2 | 37.2 | 37.2 | 43.8 | 41.1 |
T2a-c: | 43.8 | 39.6 | 56.8 | 37.2 | 37.2 | 33.0 | 19.3 |
T3a-b : | 6.3 | 14.3 | 21.6 | 20.5 | 20.5 | 22.3 | 6.8 |
T4: | 4.1 | 1.0 | 0.0 | 3.8 | 3.8 | 0.9 | 1.4 |
Missing: | 0.0 | 0.0 | 5.4 | 0.0 | 0.0 | 0.0 | 1.4 |
Regional lymph nodes clinical stage (N) (%) | |||||||
Nx-N0: | 100.0 | 98.9 | 100.0 | 92.3 | 100.0 | 100.0 | 97.3 |
N1: | 0.0 | 1.1 | 0.0 | 7.7 | 0.0 | 0.0 | 2.7 |
Missing: | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
Distance metastasis clinical stage (M) (%) | |||||||
Mx-M0: | 95.8 | 100.0 | 100.0 | 93.6 | 98.2 | 100.0 | 98.6 |
M1a-c: | 4.2 | 0.0 | 0.0 | 6.4 | 1.8 | 0.0 | 1.4 |
Missing: | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
D’Amico Classification (%) | |||||||
Low risk: | 14.6 | 50.5 | 54.1 | 32.1 | 39.3 | 36.4 | 21.9 |
Medium risk: | 27.1 | 12.1 | 29.7 | 17.9 | 23.2 | 45.5 | 34.2 |
High risk: | 58.3 | 37.4 | 16.2 | 50.0 | 37.5 | 18.1 | 42.5 |
Missing: | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.4 |
Total Gleason (%) | |||||||
2-6: | 16.7 | 73.6 | 64.9 | 68.0 | 66.9 | 36.4 | 31.5 |
7: | 29.2 | 19.8 | 29.7 | 17.9 | 18.8 | 51.5 | 43.8 |
>7: | 54.1 | 6.6 | 2.7 | 10.2 | 14.3 | 9.1 | 19.2 |
Missing: | 0.0 | 0.0 | 2.7 | 3.9 | 0.0 | 3.0 | 5.5 |
Median total Gleason ± IQR | 8.0 ± 1.0 | 6.0 ± 1.0 | 6.0 ± 1.0 | 6.0 ± 2.0 | 6.0 ± 1.0 | 7.0 ± 1.0 | 7.0 ± 1.0 |
Median time between first consultation and diagnosis in days ± IQR | 99.5 ± 139.0 | 79.0 ± 211.0 | 110.0 ± 117.0 | 78.5 ± 107.3 | 92.0 ± 99.0 | 133.0 ± 195.0 | 76.5 ± 100.0 |
Missing (%): | 0.0 | 3.3 | 5.4 | 7.7 | 4.5 | 6.1 | 1.4 |
Median time between diagnosis and first treatment in days ± IQR | 30.5 ± 127.5 | 78.0 ± 62.0 | 83.0 ± 72.0 | 104.0 ± 70.5 | 55.0 ± 66.5 | 73.5 ± 84.5 | 70.0 ± 95.0 |
Missing (%): | 0.0 | 4.4 | 0.0 | 1.3 | 6.3 | 3.0 | 2.7 |
Median time between first consultation and first treatment in days ± IQR | 164.0 ± 232.0 | 154.0 ± 207.0 | 212.0 ± 165.0 | 200.0 ± 130.0 | 166.0 ± 112.8 | 203.0 ± 149.8 | 165.0 ± 128.5 |
Missing (%): | 0.0 | 6.6 | 5.4 | 9.0 | 8.9 | 9.1 | 4.1 |