Table 6 Time interval between diagnosis and first treatment and potential determinants
Characteristic | Univariate regression | Multivariate regression | |||||||
|---|---|---|---|---|---|---|---|---|---|
Hospital random effect | Empty model ICC/MOR | 95 % CI MOR | P-value | FInal model ICC/MOR | 95 % CI MOR | P-value | |||
0.18/2.22 | 1.52–4.58 | 0.000 | 0.17/2.16 | 1.45–4.87 | 0.000 | ||||
Median (days) | IQR (days) | OR >30 days | 95 % CI OR | OR >30 days | 95 % CI OR | ||||
Age | |||||||||
<65 years | 78.0 | 74.0 | 1 | ||||||
≥65 years | 71.0 | 79.0 | 0.70 | 0.40–1.21 | 0.198 | ||||
BMI | |||||||||
<25 | 75.0 | 76.0 | 1 | ||||||
≥25 | 72.0 | 81.0 | 1.06 | 0.60–1.90 | 0.831 | ||||
Education level | |||||||||
Primary education or lower | 76.0 | 77.8 | 1 | ||||||
Graduate school or higher | 70.0 | 77.5 | 1.25 | 0.76–2.06 | 0.386 | ||||
ECOG WHO Score | |||||||||
Fully active | 77.0 | 74.8 | 1 | ||||||
Restrictive or worse | 54.0 | 77.0 | 0.55 | 0.32–0.95 | 0.033 | ||||
Specialist first consultation | |||||||||
Primary care | 76.0 | 77.0 | 1 | ||||||
Hospital or specialist | 74.0 | 79.5 | 0.86 | 0.48–1.56 | 0.621 | ||||
Primary tumour clinical stage (T) | |||||||||
T1a–T1c | 84.0 | 77.0 | 1 | ||||||
T2a–T4 | 69.0 | 79.0 | 0.59 | 0.35–0.98 | 0.040 | ||||
PSA value | |||||||||
<10 | 86.0 | 75.0 | 1 | ||||||
≥10 | 50.0 | 81.0 | 0.41 | 0.24–0.68 | 0.001 | 0.50 | 0.29–0.86 | 0.012 | |
Gleason score | |||||||||
<7 | 85.5 | 68.8 | 1 | ||||||
≥7 | 55.0 | 88.0 | 0.42 | 0.25–0.71 | 0.001 | 0.53 | 0.30–0.93 | 0.026 | |
Symptoms | |||||||||
No symptoms or discomfort | 78.0 | 72.0 | 1 | ||||||
One or more symptoms | 73.5 | 80.3 | 0.62 | 0.37–1.05 | 0.073 | ||||