Association between plasma fluorescent oxidation products and erectile dysfunction: A prospective study

BMC Urology

Table 3 Association between plasma fluorescent oxidation products (FlOPs) and erectile dysfunction in controls only (N = 460): prospective analysis in the Health Professional Follow-up Study, 1993-2001

Tertile	1	2	3	P for trend
Variables	FlOP_360			P for trend
Range (FI/ml)	< 184	≥ 184; < 233	≥ 233	---
N	164	144	152	---
Median (FI/ml)	159	206	279	---
Erectile dysfunction incidence (n, %)	55 (34 %)	51 (35 %)	51 (32 %)	---
Age adjusted	1 (ref)	1.06 (0.64, 1.75)	0.90 (0.54, 1.48)	0.59
Multivariable adjusted^a	1 (ref)	1.02 (0.58, 1.79)	0.83 (0.47, 1.47)	0.46
	FlOP_320
Range (FI/ml)	< 356	≥ 356; < 524	≥ 524	---
N	160	142	158	---
Median (FI/ml)	297	411	1858	---
Erectile dysfunction incidence (n, %)	52 (33 %)	53 (37 %)	52 (33 %)	---
Age adjusted	1 (ref)	0.96 (0.57, 1.60)	0.73 (0.44, 1.22)	0.17
Multivariable adjusted^a	1 (ref)	0.75 (0.42, 1.35)	0.55 (0.31, 0.99)	0.10
	FlOP_400
Range (FI/ml)	< 49.1	≥ 49.1; < 62.6	≥ 62.6	---
N	150	160	150	---
Median (FI/ml)	43.4	54.9	73.3	---
Erectile dysfunction incidence (n, %)	50 (33 %)	48 (31 %)	59 (39 %)	---
Age adjusted	1 (ref)	0.77 (0.46, 1.28)	1.23 (0.74, 2.03)	0.29
Multivariable adjusted^a	1 (ref)	0.72 (0.41, 1.28)	1.07 (0.60, 1.88)	0.68

Values are odds ratio (95 % confidence interval), unless otherwise specified. FI = Fluorescent intensity units
^aRisk factors include age (continuous), body mass index (continuous), alcohol intake (in quartiles: < 0.88, ≥ 0.88 and < 5.58, ≥ 5.58 and < 16.38, ≥ 16.38 g/day), physical activity (in quartiles: < 15.6, ≥ 15.6and < 30.6, ≥ 30.6 and < 56.9, ≥ 56.9 MET-hours/week), Caucasian (yes/no), fasting hours (continuous), benign prostatic hyperplasia with surgery (yes/no), history of hypertension (yes/no), history of diabetes (yes/no), smoking status (current smokers, past smokers and non-smokers), month of blood draw (in seasons: Spring [March, April and May], Summer [June, July and August], Fall [September, October and November], Winter [December, January and February]) and year of blood draw (1993, 1994 and 1995)

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