Fig. 3

Immunohistochemical staining for NEK2 expression in PCa and adjacent non-cancerous tissues (original magnification × 50). a Benign prostate tissue. b PCa with a Gleason score <8. c PCa with a Gleason score ≥8. d statistical analyses showing higher immunoreactivity scores in cancerous tissues than in adjacent non-cancerous tissues. (IRS: Ca = 4.25 ± 1.36 vs Benign = 2.93 ± 1.51, P =0.03). a, b, and c were from TMA sample NO. A5, J8, and H8, respectively