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Table 3 Pearson’s correlation coefficients between target gene (ROCK1, ROCK2 and MLCK, ROCK-to-MLCK ratios) and age using three different reference genes

From: Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle

Target gene

Reference genes

GAPDH

ACTB

PGK1

ROCK1 (n = 41)

−0.0043

−0.1584

−0.0732

only male subjects (n = 33)

−0.0375

−0.1577

−0.1596

ROCK2 (n = 41)

−0.1436

−0.0733

0.0812

only male subjects (n = 33)

−0.0884

−0.0404

0.0810

MLCK (n = 21)

0.0201

−0.4151*

0.0593

only male subjects (n = 18)

0.2899

−0.3549

0.0371

ROCK1-to-MLCK ratio (n = 21)

−0.2996

−0.3325

−0.3839*

only male subjects (n = 18)

−0.2802

−0.4389*

−0.5364*

ROCK2-to-MLCK ratio (n = 21)

−0.4757*

−0.4427*

−0.4298*

only male subjects (n = 18)

−0.4246*

−0.4694*

−0.5854**

ROCK-to-MLCK ratio (n = 21)

−0.5297**

−0.4352*

−0.5181**

only male subjects (n = 18)

−0.4625*

−0.4981*

−0.6126**

  1. Correlation coefficients in bold indicate that statistical significance was reached using all reference genes (*P < 0.05, **P < 0.01; t-test)
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BMC Urology

ISSN: 1471-2490

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