The relationship between depression and overactive bladder/urinary incontinence symptoms in the clinical OAB population

Table 5 Description of the study population

	OAB patients	Controls	p-value (adjusted for age and sex)
Demographics:
No. of subjects	51	30
Age (mean ± SD)	53.8 ± 11.9	54.2 ± 12.3	0.98
Sex (% females)	73 %	57 %	0.14
Race (% white)	43.1 %	63.3 %	0.08
Age of diagnosis of OAB (mean ± SD)	47.5 ± 15.2	Not applicable
% with OAB symptoms less than one year?	24 %	Not applicable
Urinary symptoms: (mean ± SD)
No. of daytime void (see footnote)^a	1.8 ± 1.3	0.2 ± 0.6	<0.001
No of nighttime void^b	2.6 ± 1.1	0.9 ± 0.7	<0.001
How often rush to bathroom to void?^c	2.7 ± 0.9	0.6 ± 0.7	<0.001
How often does urine leak before getting to the bathroom?^d	2.2 ± 0.9	0.3 ± 0.5	<0.001
Validated questionnaires: (mean ± SD)
ICIQ-UI (urinary incontinence, 0–21)	12.0 ± 4.9	1.4 ± 2.0	<0.001
ICIQ-OAB (overactive bladder, 0–16)	9.3 ± 2.6	2.0 ± 1.5	<0.001
OAB-q symptom bother subscale (6–36)	19.1 ± 6.6	2.2 ± 2.8	<0.001
OAB-q quality of life subscale (13–78)	29.7 ± 16.9	2.0 ± 3.0	<0.001
UDI-6 (urogenital distress inventory, 0–24)	12.6 ± 5.6	0.9 ± 1.4	<0.001
IIQ-7 (incontinence impact questionnaire, 0–28)	8.8 ± 8.2	0.1 ± 0.4	<0.001
Medical comorbidities:
Hypertension	37 %	33 %	0.72
Diabetes	8 %	3 %	0.31
Stroke, transient ischemic attack	8 %	7 %	0.15
MI, angina	0 %	0 %	1.00

Based on the categories of response on the ICIQ-OAB questionnaire
^aHow many times do you urinate during the day? 0 = 1 to 6 times, 1 = 7 to 8 times, 2 = 9 to 10 times, 3 = 11 to 12 times, 4 = 13 or more times
^bDuring the night, how many times do you have to get up to urinate, on average? 0 = none, 1 = one time, 2 = two times, 3 = three times, 4 = four or more times
^cDo you have to rush to the toilet to urinate? 0 = never, 1 = occasionally, 2 = sometimes, 3 = most of the time, 4 = all of the time
^dDoes urine leak before you can get to the toilet? 0 = never, 1 = occasionally, 2 = sometimes, 3 = most of the time, 4 = all of the time

ISSN: 1471-2490