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Table 2 Correlation between CCR7 expression and clinicopathological characteristics of bladder cancer patients

From: miR-199a-5p suppresses human bladder cancer cell metastasis by targeting CCR7

Characteristics

Total

Expression of CCR7

P value

High (n = 30)

Low (n = 10)

Age

   

0.368

  ≤ 60

22

18(81.8 %)

4(18.2 %)

 

  > 60

18

12(66.7 %)

6(33.3 %)

 

Gender

   

0.234

 Male

27

10(37 %)

17(63 %)

 

 Female

13

3(23.1 %)

10(76.9 %)

 

TNM stage

   

0.011*

 0/I

16

8(93.8 %)

1(6.2 %)

 

 II/III/IV

24

15(62.5 %)

9(37.5 %)

 

Tumor size

   

0.675

  < 3 cm

15

8(53.3 %)

7(46.7 %)

 

  ≥ 3 cm

25

22(88.8 %)

3(11.2 %)

 

Histological grade

   

0.001**

 PUNLMP/Low-grade

18

10(55.6 %)

8(44.4 %)

 

 High-grade

22

20(90.9 %)

2(9.1 %)

 

Tumor invasion depth (T)

   

<0.001**

 Tis, Ta, T1

17

10(58.8 %)

7(41.2 %)

 

 T2, T3 or above

23

20(87 %)

3(13 %)

 

Lymph node metastasis (N)

   

<0.001**

 N0

12

8(66.7 %)

4(33.3 %)

 

 N1 or above

28

22(78.6 %)

6(21.4 %)

 
  1. PUNLMP papillary urothelial neoplasm of low malignant potential; Low-grade lowgrade papillary urothelial carcinoma; High-grade high-grade papillary urothelial carcinoma (http://www.pathology.jhu.edu/bladdercancer/disease_info.cfm). TNM according to the seventh edition of staging TNM of Union Internationale Contre Le Cancer (UICC) in 2009. ** P < 0.01