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Table 2 Clinical and pathological features associated with the metastatic tumors

From: BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor

 

M0 at presentation

(N = 90)

M1

(N = 68)

Total

(N = 158)

Year of Metastasectomy

 Median

1999

1998

1999

 Range

(1991–2005)

(1990–2004)

(1990–2000)

Metastatic Site

 BONE

9 (10.0%)

10 (14.7%)

19 (12.0%)

 BOWEL

1 (1.1%)

0 (0.0%)

1 (0.6%)

 BRAIN

7 (7.8%)

4 (5.9%)

11 (7.0%)

 CONTRALATERAL ADRENAL

3 (3.3%)

5 (7.4%)

8 (5.1%)

 HEART

0 (0.0%)

1 (1.5%)

1 (0.6%)

 IPSILATERAL ADRENAL

2 (2.2%)

8 (11.8%)

10 (6.3%)

 LIVER

4 (4.4%)

5 (7.4%)

9 (5.7%)

 MUSCLE

0 (0.0%)

1 (1.5%)

1 (0.6%)

 NON-REGIONAL NODES

9 (10.0%)

1 (1.5%)

10 (6.3%)

 OMENTUM

0 (0.0%)

1 (1.5%)

1 (0.6%)

 OTHER

6 (6.7%)

8 (11.8%)

14 (8.9%)

 PANCREAS

5 (5.6%)

2 (2.9%)

7 (4.4%)

 PULMONARY

40 (44.4%)

20 (29.4%)

60 (38.0%)

 SKIN

2 (2.2%)

2 (2.9%)

4 (2.5%)

 SPLEEN

1 (1.1%)

0 (0.0%)

1 (0.6%)

 THYROID

1 (1.1%)

0 (0.0%)

1 (0.6%)

Metastatic Grade

 2

16 (17.8%)

13 (19.1%)

29 (18.4%)

 3

60 (66.7%)

36 (52.9%)

96 (60.8%)

 4

14 (15.6%)

19 (27.9%)

33 (20.9%)

Metastatic Necrosis

 No

57 (63.3%)

38 (55.9%)

95 (60.1%)

 Yes

33 (36.7%)

30 (44.1%)

63 (39.9%)

Metastatic Sarcomatoid

 No

86 (95.6%)

62 (91.2%)

148 (93.7%)

 Yes

4 (4.4%)

6 (8.8%)

10 (6.3%)