Intraoperative and postoperative feasibility and safety of total tubeless, tubeless, small-bore tube, and standard percutaneous nephrolithotomy: a systematic review and network meta-analysis of 16 randomized controlled trials

Lee, Joo Yong; Jeh, Seong Uk; Kim, Man Deuk; Kang, Dong Hyuk; Kwon, Jong Kyou; Ham, Won Sik; Choi, Young Deuk; Cho, Kang Su

doi:10.1186/s12894-017-0239-x

Table 1 Characteristics of included trials

From: Intraoperative and postoperative feasibility and safety of total tubeless, tubeless, small-bore tube, and standard percutaneous nephrolithotomy: a systematic review and network meta-analysis of 16 randomized controlled trials

Study	Year	Design	Procedures	Sample size	Age (year)	Stone burden		Tube	Stone-free rate		Quality assessment
Study	Year	Design	Procedures	Sample size	Age (year)	Size	P-value	Tube	(%)	P-value	Quality assessment
Chang et al. [41].	2011	RCT	Standard	63	58.7	24.86 ± 2.78 mm	0.722	20 Fr (7 Fr)	75%	0.51	Low
Chang et al. [41].	2011	RCT	Total tubeless	68	59.2	24.74 ± 2.69 mm		None	74%
Aghamir et al. [42].	2011	RCT	Standard	35	40	2.87 ± 0.62 cm²	0.66	NA	83%	NA	Low
Aghamir et al. [42].	2011	RCT	Total tubeless	35	38.4	2.81 ± 0.59 cm²		None	86%
Kara et al. [43].	2010	RCT	Standard	30	66.5	25.6 mm	NA	18 Fr	90%	>0.05	Low
Kara et al. [43].	2010	RCT	Total tubeless	30	67.7	22.3 mm		None	96%
Mishra et al. [44].	2010	RCT	Standard	11	42.5	2737 μL	0.18	20 Fr	81.8%	0.14	Low
Mishra et al. [44].	2010	RCT	Tubeless	11	42.3	2934.2 μL		None (6 Fr)	72.7%
Istanbulluoglu et al. [45].	2009	RCT	Standard	45	43.9	432.35 ± 195.97 mm²	0.46	14 Fr	NA	NA	Low
Istanbulluoglu et al. [45].	2009	RCT	Total tubeless	45	47.5	448.93 ± 249.13 mm²		None	NA
Crook et al. [46].	2008	RCT	Standard	25	53	17.5 mm	NA	26 Fr	84%	NA	Low
Crook et al. [46].	2008	RCT	Total tubeless	25	52	21.6 mm		None	96%
Agrawal et al. [47].	2008	RCT	Standard	101	31	NA	NA	16 Fr	100%	–	Low
Agrawal et al. [47].	2008	RCT	Tubeless	101	33	NA		None (6 Fr)	100%
Singh et al. [48].	2008	RCT	Standard	30	34	800 mm²	>0.05	22 Fr	93.3%	0.64	Moderate
Singh et al. [48].	2008	RCT	Tubeless	30	31	750 mm²		None (NA)	90%
Shah et al. [18].	2008	RCT	Small-bore tube	32	46.7	495.92 mm²	0.88	8Fr	87.5%	0.96	Low
Shah et al. [18].	2008	RCT	Tubeless	33	44.1	535.36 mm²		None (6 Fr)	87.9%
Sofikerim et al. [35].	2007	RCT	Standard	24	54.1	425 mm²	NA	24 Fr or 18 Fr	85% (24 Fr),	0.71	Moderate
Sofikerim et al. [35].	2007	RCT	Tubeless	24	47.8	428 mm²		None (6 Fr)	83% (18 Fr), 79%
Tefekli et al. [49].	2007	RCT	Standard	18	41.32	3.1 cm	NA	14 Fr	89%	>0.05	Moderate
Tefekli et al. [49].	2007	RCT	Tubeless	17	38.4	2.8 cm		None (NA)	94%
Weiland et al. [50].	2007	RCT	Small-bore tube	9	65	6.7 cm²	0.15	8.3 Fr			Moderate
Weiland et al. [50].	2007	RCT	Tubeless	9	54	3.2 cm²		None (8.2 Fr)
Choi et al. [32].	2006	RCT	Small-bore tube	12	47	32.41 mm	0.77	8.2 Fr	91.7%	0.64	High
Choi et al. [32].	2006	RCT	Tubeless	12	52.9	28.5 mm		None (6 Fr)	100%
Desai et al. [51].	2004	RCT	Standard	10	43.4	263.7 mm²	>0.05	20 Fr	100%	–	Moderate
			Small-bore tube	10	44.8	243 mm²		9 Fr	100%
			Tubeless	10	41.1	249.1 mm²		None (6 Fr)	100%
Marcovich et al. [52].	2004	RCT	Standard	20	58	3.6 cm	0.64	24 Fr		0.63	Moderate
			Small-bore tube	20	61	3 cm		8 Fr
			Tubeless	20	57	3.4 cm		None (NA)
Feng et al. [53].	2001	RCT	Standard	10	53	8.4 cm³	0.75	22 Fr	31.5%	NA	Moderate
Feng et al. [53].	2001	RCT	Tubeless	8	62	4.4 cm³		None (NA)	71.4%

NA not applicable, RCT randomized controlled trial

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