Fig. 2

Percentage distribution of patients for IPSS and OABSS urinary symptom flare after seed implant. Cutoffs for the difference between the flare peak and nadir were established. Two vertical dashed lines delineate approximately 25% and 50% of patients who experienced the urinary symptom flare assessed by the IPSS (a) and the OABSS (b). Time-course changes in total IPSS (c) and QOL (d) index scores during follow-up are plotted according to the flare peak-nadir of total IPSS (< 6, 6–10, and ≥ 12). Time-course changes in total OABSS and QOL index scores during follow-up are plotted according to the flare peak-nadir of total OABSS (< 3, 3–5, and ≥ 5). Data are plotted by means. Scores of groups with less than 6 and 6 to 10 point increases and the group with at least a 12-point increase are compared in each time point by the Mann-Whitney U-test. n.s, not significant; BL, baseline; * P < 0.05, ** P < 0.01, *** P < 0.001