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Table 2 Summary of primary and secondary outcomes

From: A retrospective feasibility study of biweekly, reduced-dose docetaxel in Asian patients with castrate-resistant, metastatic prostate cancer

Outcome

3-weekly docetaxel

(95% CI)

2-weekly docetaxel

(95% CI)

P-value

Hazard ratio

(95% CI)

P-value

Overall PSA response

  

0.683

  

 Objective responsea

12 (50.0%)

11 (45.8%)

..

..

..

 Stable disease

10 (41.7%)

9 (37.5%)

..

..

..

 Disease progression

2 (8.3%)

4 (16.7%)

..

..

..

Median response duration months, (95% CI)

4.0 (3.2–8.1)

3.7 (2.7–6.0)

0.342

  

Median TTTF, months, (95% CI)

4.5 (3.1–5.9)

3.9 (3.2–4.6)

0.542

1.2 (0.7–2.2)

0.551

Median TTP, months, (95% CI)

5.0 (3.9–6.1)

4.2 (3.5–4.9)

0.530

1.2 (0.6–2.3)

0.536

  1. Abbreviation: CI confidence interval; PSA prostate-specific antigen; TTTF time to treatment failure; TTP time to progression; PSA prostate-specific antigen
  2. Medians and 95% CIs were estimated from Kaplan-Meier analyses
  3. aObjective responses include only partial responses; no complete responses were observed