Table 2 Logistic regression results with 95% CI & p values (what factors predict PSM)
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
Variable | OR | 95% CI | p value | OR | 95% CI | p value |
Year of procedure | ||||||
2002-2009 | 1.00 | - | - | 1.00 | - | - |
2010-2012 | 1.15 | 0.76-1.73 | 0.5 | 0.72 | 0.43-1.19 | 0.2 |
2013-2014 | 1.25 | 0.79-1.96 | 0.4 | 0.37 | 0.15-0.93 | 0.03 |
Patient age at time of surgery | ||||||
Under 65 years | 1.00 | - | - | 1.00 | - | - |
65 years & above | 1.89 | 1.33-2.70 | <0.001 | 2.11 | 1.41-3.15 | <0.001 |
Pre-op PSA | ||||||
0.0-9.9 | 1.00 | - | - | 1.00 | - | - |
10.0-19.9 | 1.41 | 0.96-2.09 | 0.2 | 1.05 | 0.67-1.65 | 0.8 |
20.0 and above | 2.53 | 1.26-5.10 | 0.02 | 1.30 | 0.56-3.00 | 0.5 |
Gleason score on biopsy | ||||||
Group 1 (GS 2-6) | 1.00 | - | - | 1.00 | - | - |
Group 2 (GS 3+4) | 1.06 | 0.72-1.54 | 0.8 | 0.75 | 0.48-1.17 | 0.2 |
Group 3 (GS 4+3) | 1.35 | 0.73-2.47 | 0.4 | 0.86 | 0.43-1.69 | 0.6 |
Group 4 (GS 8) | 0.44 | 0.13-1.56 | 0.3 | 0.22 | 0.05-0.90 | 0.04 |
Group 5 (GS 9-10) | 1.77 | 0.39-8.08 | 0.6 | 0.86 | 0.15-4.89 | 0.9 |
Pathological tumour stage | ||||||
pT2 | 1.00 | - | - | 1.00 | - | - |
pT3a | 3.00 | 2.01-4.47 | <0.001 | 2.69 | 1.73-4.18 | <0.001 |
pT3b | 7.15 | 3.44-14.85 | <0.001 | 6.35 | 2.77-14.57 | <0.001 |
Median tumour volume of excised specimen | 1.16 | 1.10-1.22 | <0.001 | 1.09 | 1.03-1.16 | 0.005 |
Surgical modality | ||||||
LRP | 1.00 | - | - | 1.00 | - | - |
RARP | 1.48 | 1.03-2.13 | 0.08 | 2.52 | 1.18-5.37 | 0.02 |