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Table 4 Results of sensitivity analysis for partial and total tubeless PCNL

From: Tubeless versus standard percutaneous nephrolithotomy: an update meta-analysis

Items

No. ofstudies

Reference of studies

Sample size

Tests forheterogeneity

Analysis model

Test for overalleffect

RR/WMD/SMD

Favor

   

TB/SD

I2

Pa

 

Z

Pa

95% CI

 

Analysis of partial tubeless studies

Stone-free rate

7

[12, 20,21,22,23]

234/234

0%

0.830

Fixed

1.22

0.222

1.033[0.980,1.089]

TB

Operative time

5

[11, 12, 14, 20, 23]

118/118

57%

0.054

Random

1.20

0.229b

−3.253[−8.547,2.041]

TB

Hospital stay

7

[11,12,13, 21, 23]

316/316

99%

<0.0001

Random

4.52

<0.0001

−0.931[−1.335,-0.528]

TB

Return to normal activity

4

[11, 13, 15, 21]

226/226

0%

0.528

Fixed

24.76

<0.0001

−3.346[−3.610,-3.081]

TB

Postoperative hemoglobin drop

6

[12, 14, 15, 20, 21, 23]

290/290

48%

0.088

Fixed

1.43

0.152

−0.026[−0.063,0.010]

TB

Postoperative analgesic requirements

6

[11, 12, 14, 15, 21, 23]

286/286

65%

0.013

Random

7.33

<0.0001

−1.262[−1.600,-0.925]

TB

Postoperative pain scores

5

[11, 13,14,15, 21]

259/258

94%

<0.0001

Random

8.28

<0.0001

−20.750[−25.661,-15.839]

TB

Blood transfusion

4

[11, 13, 14, 22]

90/89

0%

0.761

Fixed

0.63

0.528

1.487[0.434,5.088]

SD

Fever

5

[14, 15, 20,21,22]

250/248

0%

0.920

Fixed

0.59

0.556

1.253[0.592,2.650]

SD

Urine leakage

4

[14, 15, 20, 21]

233/232

18%

0.303

Fixed

2.45

0.014

0.213[0.062,0.736]

TB

Analysis of total tubeless studies

Stone-free rate

4

[16, 18, 19, 24]

184/180

0%

0.650

Fixed

0.58

0.565

0.976[0.900,1.059]

SD

Operative time

4

[17, 24]

204/200

55%

0.082

Random

2.00

0.045

−3.844[−7.609,-0.078]

TB

Hospital stay

4

[17, 24]

204/200

98%

<0.0001

Random

2.20

0.028

−1.907[−3.606,-0.207]

TB

Return to normal activity

3

[18, 19, 24]

159/155

99%

<0.0001

Random

1.70

0.090

−5.855[−12.618,0.909]

TB

Postoperative hemoglobin drop

4

[17, 24]

204/200

44%

0.147

Fixed

0.53

0.597

−0.009[−0.043,0.025]

TB

Postoperative analgesic requirements

3

[18, 19, 24]

159/155

97%

<0.0001

Random

1.86

0.062

−1.502[−3.081,0.077]

TB

Postoperative pain scores

2

[19, 24]

124/120

95%

<0.0001

Random

3.01

0.003

−17.448[−28.816,-6.081]

TB

Blood transfusion

3

[17, 18, 24]

136/137

0%

0.746

Fixed

1.29

0.198

0.503[0.176,1.432]

TB

Fever

2

[17, 24]

101/102

0%

0.585

Fixed

0.55

0.583

0.745[0.260,2.133]

TB

Urine leakage

3

[17, 19, 24]

169/165

68%

0.046

Fixed

1.14

0.254c

0.351[0.058,2.122]

TB

  1. TB Tubeless percutaneous nephrolithotomy, SD Standard percutaneous nephrolithotomy, RR relative risk, WMD Weighted mean difference, SMD Standard mean difference, CI Confidence interval
  2. aP < 0.05 was considered statistically significant
  3. bOriginally significant before studies using total tubeless percutaneous nephrolithotomy were excluded
  4. cOriginally significant before studies using partial tubeless percutaneous nephrolithotomy were excluded
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BMC Urology

ISSN: 1471-2490

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