mTOR | VEGFR1 | VEGFR2 | VEGFA | HIF1A | PDGF | VHL | |
---|---|---|---|---|---|---|---|
Low (n = 18) | 0.63(1.32) | 1.96(2.10) | 3.17(6.12) | 11.87 (16.14) | 1.56 (2.27) | 5.91 (11.18) | 0.29 (1.04) |
Intermediate (n = 29) | 1.32 (5.43) | 1.84(4.85) | 1.11(1.38) | 7.10 (4.47) | 1.05 (1.29) | 4.27 (9.39) | 18.28 (87.65) |
High n = 9 | 0.55 (0.63) | 4.48(6.10) | 1.51(2.26) | 4.20 (4.58) | 3.12 (5.58) | 7.05 (9.53) | 5.18 (6.73) |
p | 0.82b | 0.37b | 0.89b | 0.18b | 0.43b | 0.76b | 0.67b |
Size ≥7 cm (n = 30) | 0.52 (1.11) | 1.74 (2.06) | 2.41 (5.14) | 10.33 (13,53) | 1.27 (1.97) | 6.62 (12.76) | 0.39 (1.20) |
Size <7 cm (n = 26) | 1.54 (5.84) | 2.69 (5.81) | 1.31 (1.72) | 6.32 (4.45) | 1.74 (3.10) | 3.56 (5.17) | 18.84 (85.70) |
p | 0.97a | 0.59a | 0.87a | 0.17a | 0.50a | 0.97a | 0.12a |
MVI absent (n = 44) | 0.45 (0.95) | 2.03(4.11) | 2.08 (4.27) | 9.77 (11.28) | 1.10(1.63) | 5.24(10.57) | 12.54(72.60) |
MVI present (n = 12) | 3.39 (9.18) | 2.75(4.76) | 1.10 (1.71) | 3.61(3.57) | 2.91(4.36) | 4.89(7.41) | 3.66(5.73) |
p | 0.25a | 0.61a | 0.46a | 0.57a | 0.08a | 0.91a | 0.68a |
Fuhrman’s Grade I e II (n = 32) | 1.43 (5.32) | 1.57 (1.79) | 2.43 (4.97) | 9.86 (13.09) | 1.54 (2.11) | 4.39 (9.21) | 0.19 (0.84) |
Fuhrman’s Grade III e IV (n = 24) | 0.40 (0.52) | 3.00 (6.10) | 1.19 (1.68) | 6.57 (4.81) | 1.45 (3.06) | 6.17 (10.97) | 20.65 (89.28) |
p | 0.81a | 0.45a | 0.56a | 0.26a | 0.89a | 0.51a | 0.13a |
Metastasis Absent (n = 48) | 0.46(0.93) | 1.81 (2.86) | 1.96 (4.14) | 8.53 (11.20) | 1.54(2.76) | 5.59 (10.78) | 1.18 (3.44) |
Metastasis Present (n = 8) | 3.64(9.71) | 4.03 (8.24) | 1.41 (2.10) | 7.98(4.54) | 1.27(1.20) | 3.05(3.04) | 54.33(151.70) |
p | 0.82a | 0.49a | 0.71a | 0.89a | 0.77a | 0.49a | 0.79a |
pT1–2 (n = 26) | 0.51 (1.16) | 1.33 (1.74) | 2.47 (5.31) | 10.12 (14.05) | 1.47 (2.13) | 7.07 (13.16) | 0.20 (0.86) |
pT3–4 (n = 30) | 1.48 (5.62) | 3.03 (5.63) | 1.33 (1.72) | 6.83 (4.67) | 1.53 (2.95) | 3.34 (4.95) | 19.00 (85.67) |
p | 0.38a | 0.51a | 0.97a | 0.26a | 0.80a | 0.16a | 0.18a |