Level of invasion into fibromuscular band is an independent factor for positive surgical margin and biochemical recurrence in men with organ confined prostate cancer

Table 1 Clinical and pathological characteristics of the patients with pT2 prostate cancer

Level of FMB	Total	Level 0	Level 1	Level 2	p value
No. of patients	461	74	243	144
Mean PSA (ng/mL)	6.6	6.5	6.5	7.0	0.672
Prostate size (cc)	36.0	37.8	35.2	36.5	0.426
Mean % of positive biopsy cores	20.2	13.0	19.0	26.2	< 0.001
Clinical stage					0.031
cT1	257	53	130	73
≥ cT2	204	21	113	71
Biopsy Gleason score, No.					< 0.001
6	197	50	104	43
3 + 4	160	19	84	57
4 + 3	71	2	38	31
8–10	33	3	17	13
Surgical Gleason score, No.					< 0.001
6	124	41	65	18
3 + 4	205	26	110	69
4 + 3	99	4	51	44
8–10	33	3	17	13
Mean PTV	8.7	3.5	8.4	11.5	< 0.001
Rate of PSM, N (%)	50 (10.8%)	4 (5.4%)	19 (7.8%)	27 (18.7%)	0.001

FMB fibromuscular band, PSA prostate specific antigen, PTV percentage of tumor volume, PSM positive surgical margin

ISSN: 1471-2490