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Table 3 Risk factors for BCR after radical prostatectomy (RP) in pT2 prostate cancer

From: Level of invasion into fibromuscular band is an independent factor for positive surgical margin and biochemical recurrence in men with organ confined prostate cancer

 

Univariate analysis

Multivariate analysis

HR (95% CI)

p value

HR (95% CI)

p value

Level of FMB

 

0.003

 

0.050

 Level 0–1

Reference

 

Reference

 

 Level 2

3.067 (1.471–6.393)

 

2.124 (1.001–4.508)

 

Surgical Gleason score

 

< 0.001

 

0.001

 6

Reference

 

Reference

 

 3 + 4

2.417 (0.1513–11.383)

0.264

1.878 (0.395–8.923)

0.428

 4 + 3

7.909 (1.770–35.348)

0.007

5.585 (1.229–25.384)

0.026

 8–10

14.099 (2.929–67.876)

0.001

10.311 (2.119–50.175)

0.004

PTV

 

0.084

  

 Lesser than 5%

Reference

   

 5–15.0%

2.421 (0.872–6.723)

0.090

  

 Greater than 15.0%

3.364 (1.150–9.841)

0.027

  

Surgical Margin Status

 

< 0.001

 

0.001

 Negative

Reference

 

Reference

 

 Positive

4.813 (2.268–10.213)

 

3.607 (1.683–7.726)

 
  1. BCR biochemical recurrence, FMB fibromuscular band, PTV percentage of tumor volume