Decolonization potential of 0.02% polyhexanide irrigation solution in urethral catheters under practice-like in vitro conditions

Table 1 Bactericidal activity of polyhexanide 0.02% solution against different reference strains

Test Sample/ Test Organism Microbial Count Control NO	Ig-reduction factor after minutes
Test Sample/ Test Organism Microbial Count Control NO	Conc. in %	5	15	30	60
Staphylococcus aureus (ATCC 6538), NO = 7.62	50.00	≥ 7.62	≥ 7.62	≥ 7.62	≥ 7.62
Staphylococcus aureus (ATCC 6538), NO = 7.62	80.00	≥ 7.62	≥ 7.62	≥ 7.62	≥ 7.62
Enterococcus hirae (ATCC 10541), NO = 7.42	50.00	≥ 7.42	≥ 7.42	≥ 7.42	≥ 7.42
Enterococcus hirae (ATCC 10541), NO = 7.42	80.00	≥ 7.42	≥ 7.42	≥ 7.42	≥ 7.42
Escherichia coli K12 (ATCC 11229), NO = 7.26	50.00	n.c.	≥ 6.56	≥ 7.26	≥ 7.26
Escherichia coli K12 (ATCC 11229), NO = 7.26	80.00	3.93	≥ 7.26	≥ 7.26	≥ 7.26
Proteus mirabilis (ATCC 14153), NO = 7.76	50.00	≥ 7.76	≥ 7.76	≥ 7.76	≥ 7.76
Proteus mirabilis (ATCC 14153), NO = 7.76	80.00	≥ 7.76	≥ 7.76	≥ 7.76	≥ 7.76
Pseudomonas aeruginosa (ATCC 15442), NO = 7.35	50.00	n.c.	5.58	≥ 7.43	≥ 7.43
Pseudomonas aeruginosa (ATCC 15442), NO = 7.35	80.00	≥ 7.35	≥ 7.43	≥ 7.43	≥ 7.43
Klebsiella pneumonia (ATCC 16609), NO = 7.66	50.00	5.18	≥ 7.66	≥ 7.66	6.96
Klebsiella pneumonia (ATCC 16609), NO = 7.66	80.00	≥ 7.66	≥ 7.66	≥ 7.66	6.96

ISSN: 1471-2490