Table 3 Clinical-pathological features of Xp11.2 tRCC patients stratified by the cut-off values of the CRP/Alb ratio and PLR

Age in years

0.011

0.015

  > 45

21 (25.6%)

15 (38.5%)

6 (14.0%)

14 (38.9%)

7 (15.2%)

  ≤ 45

61 (74.4%)

24 (61.5%)

37 (86.0%)

22 (61.1%)

39 (84.8%)

Sex

0.224

0.113

 Male

33(40.2%)

13(33.3%)

20(46.5%)

11 (30.6%)

22 (47.8%)

 Female

49(59.8%)

26(66.7%)

23(53.5%)

25 (69.4%)

24 (52.2%)

Tumor size

5.94 ± 2.65

6.7 ± 3.0

4.8 ± 2.1

0.035

7.4 ± 3.1

4.1 ± 1.2

< 0.001

Location

0.052

0.858

 Left

31(37.8%)

19 (48.7%)

12 (27.9%)

14 (38.9%)

17 (37.0%)

 Right

51(62.2%)

20 (51.3%)

31 (72.1%)

22 (61.1%)

29 (63.0%)

Symptoms

0.412

0.165

 Asymptomatic

48 (58.5%)

21 (53.8%)

27 (62.8%)

18 (50.0%)

30 (65.2%)

 Symptomatic

34 (41.5%)

18 (46.2%)

16 (37.2%)

18 (50.0%)

16 (34.8%)

Fuhrman grade

0.018

0.006

 1 to 2

32 (39.0%)

10 (25.6%)

22 (51.2%)

8 (22.2%)

24 (52.2%)

 3 to 4

50 (61.0%)

29 (74.4%)

21 (48.8%)

28 (77.8%)

22 (47.8%)

TNM stage

0.004

< 0.001

 I-II

49 (59.8%)

17 (43.6%)

32 (74.4%)

12 (33.3%)

37 (80.4%)

 III-IV

33 (40.2%)

22 (56.4%)

11 (25.6%)

24 (66.7%)

9 (19.6%)

pT status

0.018

0.006

 T1-T2

64 (78.0%)

26 (66.7%)

38 (88.4%)

22 (61.1%)

42 (91.3%)

 T3-T4

18 (22.0%)

13 (33.3%)

5 (11.6%)

14 (38.9%)

4 (8.7%)

pN status

0.003

0.003

 N0

59 (72.0%)

22 (56.4%)

37 (86.0%)

20 (55.6%)

39 (84.8%)

 N1

23 (28.0%)

17 (43.6%)

6 (14.0%)

16 (44.4%)

7 (15.2%)

pM status

0.101

0.199

 M0

78 (95.1%)

35 (89.7%)

43 (100.0%)

33 (91.7%)

45 (97.8%)

 M1

4 (4.9%)

4 (10.3%)

0 (0.0%)

3 (8.3%)

1 (2.2%)

Surgical treatment

0.502

0.686

 Radical

55 (67.1%)

23 (59.0%)

22 (51.2%)

25 (69.4%)

30 (65.2%)

 Partial

27 (32.9)

16 (41.0%)

11 (48.8%)

11 (30.6%)

16 (34.8%)

Tumour thrombus

0.011

0.001

 Negative

72 (87.8%)

30 (76.9%)

42 (97.7%)

26 (72.2%)

46 (100.0%)

 Positive

10 (12.2%)

9 (23.1%)

1 (2.3%)

10 (27.8%)

0 (0.0%)

CRP/Alb

–

< 0.001

  ≤ 0.083

44 (53.7%)

–

–

11 (30.6%)

33 (71.7%)

  > 0.083

38 (46.3%)

–

–

25 (69.4%)

13 (28.3%)

PLR

0.009

–

  ≤ 140

46(56.1%)

16 (41.0%)

30 (69.8%)

–

–

  > 140

36(43.9%)

23 (59.0%)

13 (30.2%)

–

–

LDH

0.011

0.023

 Normal

68(82.9%)

28 (71.8%)

40 (93.0%)

26 (72.2%)

42 (91.3%)

 Elevated

14(17.1%)

11 (28.2%)

3 (7.0%)

10 (27.8%)

4 (8.7%)

Proteinuria

< 0.001

< 0.001

 No

63(76.8%)

22 (56.4%)

41 (95.3%)

20 (55.6%)

43 (93.5%)

 Yes

19 (23.2%)

17 (43.6%)

2 (4.7%)

16 (44.4%)

3 (6.5%)