Table 2 Prognostic value of IER3 protein expression for the overall survival by Cox proportional hazards model

 Male vs. Female

1.14

0.62–2.10

0.681

Age

1.03

1.00–1.05

0.029

1.04

1.01–1.07

0.012

  > =pT3 vs. <=pT2

2.39

1.29–4.42

0.006

1.54

0.71–3.32

0.272

 pN(+) vs. pN(−)

3.41

1.95–5.99

< 0.001

2.35

1.26–4.38

0.007

 LVI(+) vs. LVI(−)

2.03

1.22–3.37

0.006

0.99

0.52–1.89

0.987

 PNI(+) vs. PNI(−)

1.03

0.56–1.87

0.935

 STSM(+) vs. STSM(−)

2.62

1.41–4.88

0.002

2.02

0.96–4.27

0.065

 Mets(+) vs. Mets(−)

2.35

1.41–3.97

0.001

1.81

0.98–3.33

0.058

 IER3(high) vs. IER3(low)

2.16

1.29–3.13

0.003

2.21

1.21–4.04

0.010