Fig. 3

EGFR expression is associated with drug sensitivity to cisplatin treatment. a, b TCCSUP cells were transiently transfected with varying doses of siRNA against EGFR. Knockdown of EGFR with control and EGFR-targeted siRNAs shows that proliferation in TCCSUP BC cells decreases in a dose-dependent manner (siEGFR_1, siEGFR_2, siEGFR_3). Cell proliferation assay was performed at the indicated time points (0, 6, 16, 36, or 48 h after transient transfection with siRNAs) using MTT assay at the varying time points. *p < 0.05 (Student’s t-test)