Ameliorative effects of rutin against cisplatin-induced reproductive toxicity in male rats

BMC Urology

Table 5 Effect of rutin on Antioxidant enzyme status and oxidative stress marker level in Cisplatin treated rats testis

Groups (n = 4)	CAT (U/mg protein)	SOD (U/mg protein)	POD (nmole/mg protein)	GSR (nM NADPH oxidized/min/mg tissue)	TBARS (nM/mg tissue)
Control	31.04 ± 2.96	29.75 ± 0.61	10.00 ± 1.33	28.21 ± 0.84	2.58 ± 0.75
Cisplatin	17.20 ± 1.91^a**	17.90 ± 0.61^a**	1.98 ± 0.25^a***	14.60 ± 0.67^a**	10.27 ± 0.74^a***
Cisplatin + Rutin	28.23 ± 1.79^b*	19.19 ± 1.48^a*	6.68 ± 0.69^ab*	18.86 ± 1.30^a*	7.46 ± 0.77^ab**
Rutin	23.15 ± 0.87	29.36 ± 3.48^c*	7.82 ± 0.98	28.09 ± 2.67^c*	3.06 ± 0.50^c**

Values are expressed as mean ± SEM *p < 0.05, **p < 0.01, ***p < 0.001, ^a = Value vs control, ^b = Value vs cisplatin, ^c = Value vs Cisplatin+Rutin

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