Table 4 Urinary volume, pH, solute concentrations, Ca/Cit ratio, and AP indexes in 12-h daytime and 12-h overnight urine samples of healthy and stone-forming children
Healthy children (n = 87) | Stone forming children (n = 21) | |||||
|---|---|---|---|---|---|---|
12 h day | 12 h night | p-value | 12 h day | 12 h night | p-value | |
Volume (mL/12 h) | 480 (378–708) | 360 (300–450) | < 0.001 | 650 (335–930) | 530 (315–705) | 0.192 |
Creatinine (mg/dL) | 908 (686–1250) | 1162 (835–1469) | < 0.001 | 886 (507–1393) | 1000 (611–1097) | 0.274 |
Calcium (mg/L) | 57 (38–99) | 86 (41–167) | < 0.001 | 181 (57–209) | 150 (101–258) | 0.082 |
Magnesium (mg/L) | 77 (54–110) | 151 (110–198) | < 0.001 | 79 (51–100) | 128 (55–163) | 0.021 |
Oxalate (mg/L) | 20 (15–27) | 26 (19–34) | < 0.001 | 24 (20–32) | 27 (23–37) | 0.244 |
Phosphorous (mg/L) | 630 (430–872) | 1060 (804–1414) | < 0.001 | 450 (337–664) | 870 (480–1094) | 0.001 |
Uric acid (mg/L) | 597 (431–720) | 529 (373–632) | 0.002 | 454 (266–646) | 396 (271–578) | 0.244 |
Citrate (mg/L) | 557 (405–737) | 462 (328–668) | < 0.001 | 379 (250–710) | 299 (208–477) | 0.004 |
pH | 6.60 (6.15–6.96) | 5.79 (5.60–6.22) | < 0.001 | 6.36 (6.08–7.12) | 5.91 (5.55–6.23) | 0.001 |
Ca/Cit (mg/mg) | 0.11 (0.07–0.17) | 0.21 (0.10–0.36) | < 0.001 | 0.40 (0.21–0.54) | 0.50 (0.33–0.94) | 0.002 |
AP (CaOx) index | 0.46 (0.29–0.65) | 0.67 (0.34–1.13) | < 0.001 | 1.12 (0.74–1.80) | 1.28 (0.87–2.55) | 0.052 |
AP (CaP) index | 8.24 (2.34–21.86) | 1.09 (0.16–3.04) | < 0.001 | 8.85 (1.78–62.5) | 3.03 (0.34–5.56) | 0.014 |