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Table 4 Outcomes of treatment groups

From: Definitive external-beam radiotherapy versus radical prostatectomy in clinically localized high-risk prostate cancer: a retrospective study

Treatment Outcomes

Definitive ExRT (n = 72)

RP (n = 48)

p

BF n (%)

16 (21.4)

25 (52.1)

< 0.001

Mean BFFS (months)

97.8 ± 5.9

34.4 ± 3.9

< 0.001

3 year BFFS (%) (95% CI)

89.3 (95 81.7–96.9)

50.6 (36.1–65.1)

 

5 year BFFS (%) (95% CI)

78.1 (66.7–89.5)

38.5 (20.1–56.9)

 

DM n (%)

11 (15.3)

4 (8.3)

0.399

Mean DMFS (months)

106.6 ± 5.1

118.5 ± 4.9

0.992

3-year DMFS (%) (95% CI)

93.8 (87.9–99.7)

90.9 (82.4–99.4)

 

5-year DMFS (%) (95% CI)

89.5 (81.4–97.6)

90.9 (82.4–99.4)

 

Cancer-specific mortality n (%)

5 (6.9)

2 (4.2)

0.701

Mean CSS (months)

116.9 ± 5.1

109.9 ± 14.0

0.693

3 year CSS (%)

96.8 (92.5–100.0)

96.9 (90.8–100.0)

 

5 year CSS (%)

94.1 (87.2–100.0)

96.9 (90.8–100.0)

 

All-cause mortality n (%)

9 (12.5)

7 (14.6)

0.788

Mean OS (months)

110.9 ± 4.6

92.3 ± 13.4

0.160

3 year OS (%) (95% CI)

94.1 (88.4–99.7)

87.2 (76.6–97.9)

 

5 year OS (%) (95% CI)

86.8 (77.2–96.3)

87.2 (76.6–97.9)

 
  1. ExRT, external-beam radiotherapy; RP, radical prostatectomy; BF, biochemical failure; BFFS, biochemical failure free survival; DM, distant metastasis; DMFS, distant metastasis free survival; CSS, cancer-specific survival; OS, overall survival