BMC Urology

Table 5 Possible predictive factors in univariate and multivariate analysis

From: Definitive external-beam radiotherapy versus radical prostatectomy in clinically localized high-risk prostate cancer: a retrospective study

	OR	95% CI	p
All patients-univariate
Age	0.96	0.92–1.00	0.066+
PSA ≥20 ng/mL	1.26	0.66–2.41	0.480
Clinical ≥T3 stage	0.70	0.35–1.41	0.319
GS ≥8 at biopsy	1.29	0.69–2.42	0.430
Treatment group RP	4.61	2.36–9.00	< 0.001*
All patients-multivariate
PSA ≥20 ng/mL	1.85	0.95–3.59	0.069+
Treatment group RP	5.35	2.69–10.61	< 0.001*
ExRT group-univariate
ADT use < 2-year	1.98	0.72–5.49	0.188
No PLI	2.53	0.93–6.91	0.071+
ExRT group-multivariate
ADT use < 2-year	2.42	0.85–6.89	0.098
No PLI	2.87	1.01–8.16	0.048*
RP group-univariate
Positive surgical margin	2.41	1.00–5.78	0.050*
Pathological N1 stage	1.97	0.87–4.46	0.105
Pathological ≥T3 stage	2.17	0.65–7.32	0.210
GS ≥8 at RP specimen	1.83	0.80–4.18	0.154
RP group-multivariate
Positive surgical margin#	2.41	1.00–5.78	0.050*

OR, Odds ratio; CI, confidence Interval; PSA, prostate specific antigen; GS, Gleason score; RP, radical prostatectomy; ExRT, external-beam radiotherapy; ADT, androgen deprivation treatment; PLI, pelvic lymphatic irradiation
*indicates statistically significant data; + indicates borderline significant data
#, for the RP group, positive surgical margin was the only significant risk factor predicting BF in multivariate analysis

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ISSN: 1471-2490

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