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Fig. 3 | BMC Urology

Fig. 3

From: Unbiased data mining identifies cell cycle transcripts that predict non-indolent Gleason score 7 prostate cancer

Fig. 3

The positive predictors of BCR in Gleason score 7 tumours also predict castration-resistant prostate cancer (CRPC). Ten of 11 positive predictors identified in this study encode cell cycle and mitosis proteins that are part of a HES6-associated E2F1-dependent signature of castration-resistant prostate cancer (CRPC). Four of the 10 are targeted by the miRNA miR-145-3p in CRPC. Total of numbers within or adjacent to each circle are the number of prognostic transcripts in each dataset

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BMC Urology

ISSN: 1471-2490

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