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Table 3 Multivariate Cox regression analysis of factors predictive of prognosis in bladder cancer after radical cystectomy

From: Association between De Ritis ratio (aspartate aminotransferase/alanine aminotransferase) and oncological outcomes in bladder cancer patients after radical cystectomy

Parameters

HR

95% CI

P

HR

95% CI

P

Parameters

HR

Multivariate Cox proportional analysis to metastasis

Age (< 70 vs. ≥70)

0.994

0.959

1.030

0.725

0.998

0.964

1.033

0.894

Gender (male vs. female)

0.825

0.354

1.923

0.655

0.745

0.288

1.928

0.544

BMI

0.972

0.867

1.088

0.618

0.957

0.854

1.073

0.450

Pathologic T stage

1.667

1.234

2.251

0.001

1.776

1.296

2.434

< 0.001

Lymph node involvement

1.727

0.895

3.335

0.103

1.816

0.942

3.501

0.075

Grade

0.640

0.078

5.249

0.678

0.549

0.065

4.629

0.582

De Ritis ratio (Low vs. high)

2.389

1.161

4.914

0.018

    

De Ritis ratio (Continuous)

    

1.582

1.129

2.219

0.008

Multivariate Cox proportional analysis of cancer-related death

Age (< 70 vs. ≥70)

0.996

0.959

1.035

0.834

1.000

0.964

1.038

0.988

Gender (male vs. female)

0.488

0.164

1.448

0.196

0.363

0.096

1.377

0.136

BMI

0.941

0.825

1.073

0.361

0.919

0.807

1.046

0.200

Pathologic T stage

1.841

1.297

2.612

0.001

1.933

1.342

2.784

< 0.001

Lymph node involvement

1.613

0.775

3.358

0.201

1.708

0.823

3.546

0.151

Grade

0.584

0.069

4.149

0.589

0.461

0.051

5.286

0.685

De Ritis ratio (Low vs. high)

2.755

1.214

6.249

0.015

    

De Ritis ratio (Continuous)

    

1.848

1.239

2.755

0.003

Multivariate Cox proportional analysis of overall death

Age (< 70 vs. ≥70)

0.999

0.963

1.037

0.956

1.004

0.969

1.041

0.807

Gender (male vs. female)

0.471

0.161

1.377

0.169

0.337

0.088

1.285

0.111

BMI

0.972

0.858

1.100

0.651

0.952

0.840

1.078

0.436

Pathologic T stage

1.921

1.368

2.698

< 0.001

2.017

1.415

2.876

< 0.001

Lymph node involvement

1.572

0.778

3.176

0.207

1.694

0.842

3.409

0.139

Grade

0.326

0.065

5.372

0.538

0.556

0.064

4.718

0.538

De Ritis ratio (Low vs. high)

2.761

1.257

6.067

0.011

    

De Ritis ratio (Continuous)

    

1.860

1.262

2.743

0.002

  1. HR hazard ratio, CI confidence interval, BMI body mass index