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Fig. 4 | BMC Urology

Fig. 4

From: Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel

Fig. 4

The effects of Ca2+ free solution and nifedipine on the basal muscle tone and spontaneous contractions in TREK-1 KO mice. a Representative traces of muscle tone and spontaneous activity in BSM strips from WT (upper panels) and TREK-1 KO (lower panels) animals. b Application of additional stretch under Ca2+ free conditions reduced the amplitude of the contractile response in both WT and TREK-1 KO animals

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