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Fig. 6 | BMC Urology

Fig. 6

From: Sustained density of neuroendocrine cells with aging precedes development of prostatic hyperplasia in spontaneously hypertensive rats

Fig. 6

Density of NE cells in the epithelium of ventral prostatic ducts. Grey columns, SHR; white columns, WKY. The density of serotonin-positive NE cells to all epithelial cells (mean ± SE) (%) in SHR vs. WKY were 3.25 ± 0.44 vs. 3.37 ± 0.64 in 8-week old rats (p = 0.882), 2.77 ± 0.12 vs. 2.30 ± 0.39 in 12-week old rats (p = 0.117), 2.95 ± 0.12 vs. 1.58 ± 0.21 in 16-week old rats (p < 0.001), 2.29 ± 0.29 vs. 1.42 ± 0.30 in 28-week old rats (p = 0.069) and 1.75 ± 0.43 vs. 0.90 ± 0.14 in 56-week old rats (p = 0.043). The density of NE cells in the VPd decreased with aging in the WKY group, whereas it was sustained by 16 weeks old, then decreased with aging in the SHR group. There was the most remarkable difference in the density between the two groups at 16 weeks old (p < 0.001)

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BMC Urology

ISSN: 1471-2490

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