Fig. 5
From: miR-185 inhibits prostate cancer angiogenesis induced by the nodal/ALK4 pathway
Overexpression of miR-185 exerted antitumour activity against tumour growth in nude mice. a The macroscopic appearance of the dissected tumour tissues 30 days after the treatments. b The tumour size was calculated in nude mice subjected to specific treatments. c The tumour weight was calculated in nude mice subjected to specific treatments. d Protein levels of VEGF were assessed by Western blot in nude mice treated with specific treatments. e The distribution of CD31 was detected by immunohistochemistry. Scale bar: 50 μM. The data represent one of three independent experiments. Error bars denote the mean ± SD. *P < 0.05, **P < 0.01