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Table 1 Patient characteristics (n = 52)

From: The neutrophil-lymphocyte ratio has a role in predicting the effectiveness of nivolumab in Japanese patients with metastatic renal cell carcinoma: a multi-institutional retrospective study

Characteristic

 

N (%)

Sex

Male

36 (69)

Female

16 (31)

Prior nephrectomy

Yes

45 (87)

No

7 (13)

Age at start of nivolumab

Median (range)

67.0 (38–86)

ECOG PS

0

35 (67)

1

15 (29)

2

2 (4)

Histologic type

Clear cell carcinoma

42 (81)

Non-clear cell carcinoma

6 (11)

Unknown

4 (8)

Treatment line of nivolumab

Second

18 (35)

Third line or later

34 (65)

IMDC risk classification

Favorable

8 (15)

Intermediate

37 (71)

Poor

7 (14)

Number of metastatic sites

< 3

31 (60)

≥3

21 (40)

CRP at baseline

< 10 mg/L

29 (56)

≥10 mg/L

23 (44)

NLR at baseline

< 3

20 (39)

≥3

32 (61)

NLR at 4 weeks

< 3

20 (39)

≥3

31 (59)

unknown

1 (2)

  1. ECOG Eastern Cooperative Oncology Group; PS Performance status; IMDC International Metastatic Renal Cell Carcinoma Database Consortium; CRP C-reactive protein; NLR Neutrophil-to-lymphocyte ratio