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Table 2 Peri-operative outcomes

From: External validation of the Simplified PADUA REnal (SPARE) nephrometry system in predicting surgical outcomes after partial nephrectomy

  Total Low risk (0–3) Intermediate risk (4–7) High risk (8–10) P-value
Ischemia time, minutes 24 (11) 22 (10) 27 (13) 28 (13) < 0.001
Operative time, minutes 227 (97) 210 (109) 234 (80.5) 265 (67) 0.003
EBL, mL 150 (250) 100 (250) 150 (212.5) 200 (175) 0.59
Complications     0.03
 minor, Clavien-Dindo grade 2 or less 49 (23.7) 28 (23.3) 18 (24.3) 3 (23)  
 major, Clavien-Dindo grade 3 or more 8 (3.9) 7 (5.8) 0 (0) 1 (7.7)  
Length of stay, days 8 (2) 7 (3) 8 (2) 8 (2.5) 0.02
ACE-3rd day 11 (21) 8.5 (21) 13.5 (24.25) 20 (30) 0.008
PCE-3rd day 14 (23) 10.5 (23) 17.5 (26.75) 22 (30) 0.005
ACE-30th day 8 (15) 4 (16) 9.5 (14) 17 (11) 0.007
PCE-30th day 10 (17) 6.5 (18) 11.5 (13.5) 16 (12.5) 0.018
ACE-1st year 12 (18) 8.5 (16) 14.5 (17.25) 29 (18.5) < 0.001
PCE-1st year 14.9 (18.2) 11.8 (18.8) 17 (16.5) 34 (16.8) < 0.001
CKD upstaging 30 (14.5) 16 (13.3) 10 (13.5) 4 (30.8) 0.22
Pathological features      0.45
 clear cell RCC 95 (45.9) 52 (43.3) 37 (50) 6 (46.2)  
 papillary RCC 18 (8.7) 10 (8.3) 7 (9.5) 1 (7.7)  
 chromophobe RCC 17 (8.2) 7 (5.8) 9 (12.2) 1 (7.7)  
 others 7 (3.4) 3 (2.5) 3 (4.1) 1 (7.7)  
 oncocytoma 8 (3.9) 3 (2.5) 4 (5.4) 1 (7.7)  
 angiomyolipoma 62 (30) 45 (37.5) 14 (18.9) 3 (23.1)  
Positive surgical margin 8 (3.9) 6 (5) 1 (1.4) 1 (7.7) 0.24
Achievement of trifecta 112 (54.1) 73 (60.8) 35 (47.3) 3 (23.1) 0.02
Achievement of pentafecta 51 (24.6) 43 (35.8) 8 (10.8) 0 (0) 0.01
  1. Data are expressed as median (IQR), or n (%)
  2. EBL estimated blood loss, ACE absolute change of estimated glomerular filtration rate, PCE percent change of estimated glomerular filtration rate, CKD chronic kidney disease, RCC renal cell carcinoma