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Table 3 Comparison of adverse effects between two treatments types with intravesical bacillus Calmette–Guérin

From: Impact of maintenance therapy using a half dose of the bacillus Calmette–Guérin Tokyo strain on recurrence of intermediate and high-risk nonmuscle invasive bladder cancer: a retrospective single-center study

 

ALL (n = 78)

Induction (n = 40)

Maintenance (n = 38)

P value

Adverse effects (%)

    

Grade ≤ 2/Grade ≥ 3

39 (50.0)/0

13 (32.5)/0

26 (68.4)/0

0.003

Local

30 (38.6)

9 (22.5)

21 (57.9)

0.003

Systemic

16 (20.5)

7 (17.5)

9 (23.7)

0.50

Both

7 (9.0)

3 (7.5)

4 (10.5)

0.64

Local symptoms (%)

    

Miction pain

18 (23.1)

4 (10.0)

14 (36.8)

 < 0.001

Pollakiuria

8 (10.3)

3 (7.5)

5 (13.2)

0.41

Hematuria

6 (7.7)

1 (2.5)

5 (13.2)

0.10

Residual urine

2 (2.6)

0

2 (5.3)

0.23

Urgent urination

1 (1.3)

1 (2.5)

0

0.33

Systemic symptoms (%)

    

Arthralgia

1 (1.3)

1 (2.5)

0

0.33

Fever

15 (19.2)

6 (15.0)

9 (23.7)

0.40

Rash

1 (1.3)

1 (2.5)

0

0.33

  1. Unless otherwise stated, values are numbers of patients with percentages in parentheses