Table 3 Baseline clinical characteristics of participants by study arm
Clinical characteristics | Low dose group, 2 × 1 mg PAC (n = 73) | High dose group, 2 × 18.5 mg PAC (n = 72) | P value* |
|---|---|---|---|
Number of episodes of UTI in the past 6 months** | 0.816 | ||
1 | 13 (17.8) | 8 (11.1) | |
2 | 34 (46.6) | 37 (51.4) | |
3 | 17 (23.3) | 16 (22.2) | |
4 | 6 (8.22) | 7 (9.7) | |
≥ 5 | 3 (4.11) | 4 (5.6) | |
Number of episodes of UTI in the past 12 months | 0.249 | ||
2 | 13 (17.8) | 7 (9.72) | |
3 | 22 (30.1) | 29 (40.3) | |
4 | 11 (15.1) | 15 (20.8) | |
≥ 5 | 27 (37.0) | 21 (26.17) | |
Frequency of sexual intercourse (per week) | 0.304 | ||
≤ 1 | 22 (30.1) | 14 (19.4) | |
2–4 | 34 (46.6) | 41 (56.9) | |
5–6 | 10 (13.7) | 13 (18.1) | |
≥ 7 | 7 (9.6) | 4 (5.6) | |
Number of sexual partners | 0.256 | ||
0 | 5 (6.9) | 1 (1.4) | |
1 | 67 (91.8) | 70 (97.2) | |
2 | 1 (1.4) | 1 (1.4) | |
Stability in sexual relations | 0.987 | ||
No stability | 3 (4.1) | 2 (1.4) | |
Stable in the past month | 7 (9.6) | 6 (8.3) | |
Stable in the past 6 months | 16 (21.9) | 15 (20.8) | |
Stable in the past year | 46 (63.0) | 48 (66.7) | |
Prefer not to respond | 1 (1.4) | 1 (1.4) | |
New partner in last month | 4 (5.5) | 5 (6.9) | 0.715 |
Type of Contraception | 0.373 | ||
Hormonal contraception | 43 (58.9) | 53 (73.6) | |
Spermicide | 1(1.4) | 0 | |
Non hormonal IUD | 7 (9.6) | 4 (5.6) | |
Condom | 17 (23.3) | 11 (15.3) | |
None | 5 (6.8) | 4 (5.6) | |
First UTI before age 15 | 15 (20.6) | 16 (22.2) | 0.839 |
Maternal history of UTI | 38 (52.1) | 43 (59.7) | 0.352 |
Personal history of recurrent UTI*** | 0.775 | ||
< 1 year | 4 (8.2) | 2 (4.3) | |
1–2 years | 9 (18.4) | 12 (25.5) | |
3–5 years | 15 (30.6) | 15 (31.9) | |
6–10 years | 14 (28.6) | 10 (21.3) | |
> 10 years | 7 (14.3) | 8 (17.0) | |
Missing data | 24 | 25 | |
Hydration (average litres of water per day)*** | 0.147 | ||
Mean ± SD | 1.62 ± 0.75 | 1.81 ± 0.63 | |
< 1 | 9 (15.8) | 4 (7.0) | |
≥ 1–2 | 30 (52.6) | 27 (47.4) | |
> 2–3 | 13 (22.8) | 23 (40.4) | |
≥ 3 | 5 (8.8) | 3 (7.0) | |
Missing data | 16 | 15 | |
Alcohol consumption (per week)*** | 0.140 | ||
< 1 | 7 (12.7) | 15 (25.9) | |
1–3 | 28 (50.9) | 21 (36.2) | |
> 4 | 20 (36.4) | 22 (37.9) | |
Missing data | 18 | 14 | |
Tobacco use*** | 0.448 | ||
Smoker | 5 (8.8) | 3 (5.2) | |
Non-smoker | 52 (91.2) | 55 (94.8) | |
Missing data | 16 | 14 |