Fig. 1

Expression levels of hTERT, KRT7, and SVV mRNA in 80 bladder cancer patients. a Heat map representation of the three mRNA expression levels in the 80 bladder cancer urine samples. b Comparison of hTERT, KRT7, and SVV mRNA levels in the urine samples of bladder cancer and non-bladder cancer patients. c Receiver operating characteristic (ROC) curves were performed to determine the area under the ROC curve (AUC), sensitivity, specificity, as well as the likelihood ratios (LR⁺ and LR⁻) to determine the levels of the biomarkers that best differentiate the bladder cancer cases versus the control subjects. The optimal cut-off values were calculated as the marker level that maximizes the sensitivity and specificity