Table 3 Overall sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy for cytology, hTERT, KRT7, and SVV when tested independently or in combinations in the voided urine samples of bladder cancer patients
Sensitivity | Specificity | PPV | NPV | Accuracy | |
|---|---|---|---|---|---|
Cytology | 31.3 | 100.0 | 100.0 | 42.1 | 54.2 |
hTERT | 81.3 | 97.5 | 98.5 | 72.7 | 87.5 |
KRT7 | 91.3 | 85.0 | 92.4 | 82.9 | 89.2 |
SVV | 72.5 | 90.0 | 93.5 | 62.1 | 78.3 |
Cyt + hTERT | 85.0 | 100.0 | 100.0 | 74.1 | 88.3 |
Cyt + KRT7 | 95.0 | 85.0 | 92.7 | 89.5 | 91.7 |
Cyt + SVV | 77.5 | 90.0 | 93.7 | 63.2 | 79.2 |
hTERT + KRT7 | 100.0 | 85.0 | 93.0 | 100.0 | 95.0 |
hTERT + SSV | 95.0 | 90.0 | 94.9 | 87.8 | 92.5 |
KRT7 + SVV | 93.8 | 75.0 | 88.2 | 85.7 | 87.5 |
Cyt + hTERT + KRT7 | 100.0 | 85.0 | 93.0 | 100.0 | 95.0 |
Cyt + hTERT + SSV | 96.3 | 90.0 | 95.0 | 90.0 | 93.3 |
Cyt + KRT7 + SSV | 96.3 | 75.0 | 88.5 | 90.9 | 89.2 |
hTERT + KRT7 + SVV | 100.0 | 75.0 | 88.9 | 100.0 | 91.7 |
Cyt + hTERT + KRT7 + SVV | 100.0 | 75.0 | 88.9 | 100.0 | 91.7 |