Fig. 2
Examples of inflammation scoring (grade). All tissues were stained with haematoxylin–eosin and examined at 10X (a-j) or 4X (k) magnification. a No signs of inflammatory cells. b Individual inflammatory cells (arrows) separated by distinct interventing spaces are seen around the glands (< 100 cells/mm2). c Confluent sheets of inflammatory cells (arrowhead) around the glands without tissue destruction or lymphoid nodule/follicle formation (100–500 cells/mm2). d Confluent sheets of inflammatory cells with lymphoid nodule formation (arrow) lie within stroma around the glands (> 500 cells/mm2). e No signs of inflammatory cells. f Few inflammatory cells (arrow) seen around the glands (< 100 cells/mm2). g Confluent sheets of inflammatory cells (arrowheads) around the glands without tissue destruction or lymphoid nodule/follicle formation (100–500 cells/mm2). h Confluent sheets of inflammatory cells with lymphoid nodule formation (arrows) lie within stroma around the glands (> 500 cells/mm2). i. No signs of inflammation. j Urinary bladder surface epithelium is partially diminished (arrow) and few inflammatory cells (arrowhead) are seen under urothelium in the lamina propria (< 100 cells/mm2). k Urinary bladder surface epithelium is totally diminished (arrows), and there is lymphoid cell infiltration in the lamina propria and through the bladder wall (arrowheads) without tissue destruction or lymphoid nodule/follicle formation (100–500 cells/mm2). The scale bar in each image indicates 200 µm