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Table 1 Immunohistochemical grading scales

From: Cross-organ sensitization between the prostate and bladder in an experimental rat model of lipopolysaccharide (LPS)-induced chronic pelvic pain syndrome

Grade (Inflammatory cell density, cells/mm2)  
0 No inflammation
1, mild Individual inflammatory cells (< 100 cells/mm2)
2. moderate Confluent sheets of inflammatory cells without tissue destruction or lymphoid follicle formation (100–500 cells/mm2)
3, severe Confluent sheets of inflammatory cells with tissue destruction or lymphoid follicle formation (> 500 cells/mm2)
Extent (Tissue area involved by inflammatory cell infiltrates)  
1, focal  < 10%
2, multifocal 10–50%
3, diffuse  > 50%
  1. Grading scales used to score inflammatory changes in prostate and urinary bladder. The procedure for determination of grade and extent of inflammation was adapted from Inamura et al. [21]