Skip to main content

Table 1 Relevant literature on testicular involvement in syphilis

From: Hard bilateral syphilitic testes with vasculitis: a case report and literature review

Case number Authors Age (years) Testicular findings Systemic findings
1 Lees et al. 1937 [15] 27 Bilateral (first right scrotal swelling, then left scrotal swelling)
Congenital syphilis
NA
2 London et al. 1947 [17] 33 Hardening with painful swelling of testes NA
3 Al-Egaily et al. 1977 [1] 37 Bilateral firm and enlarged testis with painless penile sores NA
4–9 Archimbaud et al. 1984 [5]   Six cases NA
10 Onishi et al. 1987 [18] 72 Right scrotal swelling with tenderness Aortic aneurysm
Aortitis
11 Terao et al. 1993 [19] 44 Enlarged firm right testis NA
12 Nakano et al. 1999 [20] 75 Painless left scrotal swelling NA
13 Varma et al. 2009 [21] 39 Right testis painful and firm lump HIV
14 Silva et al. 2010 [22] 32 Bilateral testicular swelling NA
15 Nakano et al. 2011 [8] 47 Painful right testicular swelling NA
16 Sekita et al. 2012 [23] 40 Left scrotal swelling
Left testis
NA
17 Teo et al. 2012 [14] 47 Right testis with firm, non-tender swelling
Non-ulcerated indurated subprepuce
Conservative treatment with doxycycline
NA
18 Liang et al. 2013 [24] 37 Left testicle and left kidney
Painless swelling
Doxycycline coz of penicillin allergy post-operation
HIV
19 Yogo et al. 2014 [25] 28 Right testis pain and swelling
Jarisch–Herxheimer reaction in the testis following Penicillin G infusion
HIV with Bilateral Retinal detachment
20 Morlacco et al. 2015 [26] 31 Right testis pain and swelling NA
21 Chu et al. 2016 [27] 33 Right testis hardening and swelling
Non-granulomatous type
HIV
22 Tagliati et al. 2020 [13] 39 Testicular discomfort
Multiple bilateral subcentimetric hypoechoic lesions
NA
23 Agrawal et al. 2020 [28] 40 Left scrotal abscess due to epididymo-orchitis
Ulcerated enlarged left testis with indurated base
HIV
24 Our case 63 Bilateral testes induration Aortitis
Left subclavian artery aneurysm
  1. HIV human immunodeficiency virus, NA not applicable