Table 1 Relevant literature on testicular involvement in syphilis
From: Hard bilateral syphilitic testes with vasculitis: a case report and literature review
Case number | Authors | Age (years) | Testicular findings | Systemic findings |
|---|---|---|---|---|
1 | Lees et al. 1937 [15] | 27 | Bilateral (first right scrotal swelling, then left scrotal swelling) Congenital syphilis | NA |
2 | London et al. 1947 [17] | 33 | Hardening with painful swelling of testes | NA |
3 | Al-Egaily et al. 1977 [1] | 37 | Bilateral firm and enlarged testis with painless penile sores | NA |
4–9 | Archimbaud et al. 1984 [5] | Six cases | NA | |
10 | Onishi et al. 1987 [18] | 72 | Right scrotal swelling with tenderness | Aortic aneurysm Aortitis |
11 | Terao et al. 1993 [19] | 44 | Enlarged firm right testis | NA |
12 | Nakano et al. 1999 [20] | 75 | Painless left scrotal swelling | NA |
13 | Varma et al. 2009 [21] | 39 | Right testis painful and firm lump | HIV |
14 | Silva et al. 2010 [22] | 32 | Bilateral testicular swelling | NA |
15 | Nakano et al. 2011 [8] | 47 | Painful right testicular swelling | NA |
16 | Sekita et al. 2012 [23] | 40 | Left scrotal swelling Left testis | NA |
17 | Teo et al. 2012 [14] | 47 | Right testis with firm, non-tender swelling Non-ulcerated indurated subprepuce Conservative treatment with doxycycline | NA |
18 | Liang et al. 2013 [24] | 37 | Left testicle and left kidney Painless swelling Doxycycline coz of penicillin allergy post-operation | HIV |
19 | Yogo et al. 2014 [25] | 28 | Right testis pain and swelling Jarisch–Herxheimer reaction in the testis following Penicillin G infusion | HIV with Bilateral Retinal detachment |
20 | Morlacco et al. 2015 [26] | 31 | Right testis pain and swelling | NA |
21 | Chu et al. 2016 [27] | 33 | Right testis hardening and swelling Non-granulomatous type | HIV |
22 | Tagliati et al. 2020 [13] | 39 | Testicular discomfort Multiple bilateral subcentimetric hypoechoic lesions | NA |
23 | Agrawal et al. 2020 [28] | 40 | Left scrotal abscess due to epididymo-orchitis Ulcerated enlarged left testis with indurated base | HIV |
24 | Our case | 63 | Bilateral testes induration | Aortitis Left subclavian artery aneurysm |