Presepsin as a predictor of septic shock in patients with urinary tract infection

BMC Urology

Table 4 Prediction of SIRS on the 5th day by logistic regression analysis

Variable	Univariate analysis			Multivariable analysis
Variable	P-value	HR	95% CI	P-value	HR	95% CI
Day1/WBC (4000–12,000 or other)	0.19
Day1/CRP (≥ 10 or < 10)	0.280
Day1/Presepsin (≥ 500 or < 500)	0.049	9.176	1.013–83.108	0.366
Day1/PCT (≥ 2 or < 2)	0.012	17.455	1.886–161.528	0.012	17.455	1.886–161.528
Day1/AST (≥ 34 or < 34)	0.079
Day1/ALT (≥ 28 or < 28)	0.283
Day1/γGPT (≥ 47 or < 47)	0.177
Day1/Cr (male; ≥ 1.07 or < 1.07, female; ≥ 0.79 or < 0.79)	0.998
Day3/WBC (4000–12,000 or other)	0.120
Day3/CRP (≥ 10 or < 10)	0.998
Day3/Presepsin (≥ 500 or < 500)	0.067
Day3/PCT (≥ 2 or < 2)	0.998
Sex (male or female)	0.596
Urinary culture (P vs N)	0.999
Blood culture (P vs N)	0.059
Placement of urinary catheter (Y vs N)	0.280
Urological cancer (Y vs N)	0.346
Urinary calculi (Y vs N)	0.040	5.833	1.084–31.377	0.182
DM (Y vs N)	0.783
Surgical procedure (Y vs N)	0.120
Internal use of steroid (Y vs N)	0.439

WBC white blood cell, CRP C-reactive protein, PCT procalcitonin, AST aspartate transaminase, ALT alanine transaminase, γGTP γ-glutamyl transpeptidase, Cr creatinine, DM diabetes mellitus, P positive, N no, Y yes

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