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Table 7 Risk factor analysis of progression in 3 years after RNU

From: Risk factor analysis of intravesical recurrence after retroperitoneoscopic nephroureterectomy for upper tract urothelial carcinoma

Variables

 

No progression

n = 40 (%)

Progression

n = 10 (%)

p-value

Age (years)

 ≥ 70

24 (60.0)

7 (70.0)

0.7222

Gender

Male

29 (72.5)

8 (80.0)

1.0000

Laterality

Right

17 (42.5)

6 (60.0)

0.4804

Location of main tumor

Ureter

19 (47.5)

6 (60.0)

0.7252

Hydronephrosis

Yes

12 (30.0)

3 (30.0)

1.0000

Urine cytology

Positive

19 (47.5)

5 (50.0)

1.0000

Urinary BTA

Positive

18 (45.0)

3 (30.0)

0.4880

Urinary NMP22

Positive

18 (45.0)

5 (50.0)

1.0000

Diagnostic ureteroscopic biopsy

Yes

12 (30.0)

3 (30.0)

1.0000

Multifocality

Multiple

4 (10.0)

0 (0.0)

0.5710

Tumor size (cm)

 ≥ 3

14 (35.0)

8 (80.0)

0.0836

Pathological T stage

 ≥ 3

8 (20.0)

8 (80.0)

0.0007*

Grade

3

22 (55.0)

9 (90.0)

0.0145*

LVI

Positive

6 (15.0)

6 (60.0)

0.0073*

INF

b, c

28 (70.0)

10 (100.0)

0.0920

Pneumoretroperitoneum time (min)

 ≥ 210

20 (50.0)

5 (50.0)

1.0000

Total operating time (min)

 ≥ 360

19 (47.5)

5 (50.0)

1.0000

ASC

Yes

12 (30.0)

8 (80.0)

0.0088*

  1. BTA bladder tumor antigen, NMP22 nuclear mitotic apparatus protein, LVI lymphovascular invasion, INF infiltrative growth, ASC adjuvant systemic chemotherapy
  2. *p < 0.05